60 Minutes Story on Resveratrol - Clip 2 of 2
Resveratrol has been tested on mice and the results have been encouraging. In a test-video provided by Sirtris, two mice were fed a high fat diet for 12 weeks. But when placed on a treadmill, one mouse ran twice as far. He was given high concentrations of resveratrol.
"You have fat mice, and you have fat mice with resveratrol. And the ones that are on resveratrol, they can run twice as far, and they live longer, about 20 percent longer," Sinclair says.
Other studies showed that among mice fed a high fat diet, those taking resveratrol didn't gain as much weight as those not given the drug. Sinclair believes that resveratrol actually changes the physiology of the mice.
The proof, he says, is in the post-mortems. "Their organs looked pristine, youthful, fat-free, and their physiology was just like they were dieting. But they were fat."
Convinced that they were on the right path, they fast-tracked the drug into human trials on people with untreated diabetes. The results were impressive: it significantly lowered glucose and insulin levels, without the patients changing their diet or taking any other drugs.
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